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|Flybase description||The gene Suppressor of profilin 2 is referred to in FlyBase by the symbol Dmel\Sop2 (CG8978, FBgn0001961).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: female germline ring canal stabilization; actin filament-based process; pseudocleavage involved in syncytial blastoderm formation; actin filament reorganization involved in cell cycle; positive regulation of filopodium assembly; bristle morphogenesis; cytoplasmic transport, nurse cell to oocyte; axonal fasciculation; axonogenesis; compound eye morphogenesis.
14 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; filopodium; mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Actin-related protein 2/3 complex, subunit 1; WD40 repeat; WD40 repeat 2; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.