Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Gli
Flybase description The gene Gliotactin is referred to in FlyBase by the symbol Dmel\Gli (CG3903, FBgn0001987).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.5054 -0.4707 -4.254095 -5.9754 -5.780451 -4.8537 -1.85864 -3.837067
    Affimetrix absolute value 7.085 7.46 6.095 5.854 6.233 6.293 7.689 6.33
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: carboxylesterase activity.
There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; maintenance of imaginal disc-derived wing hair orientation; establishment of blood-nerve barrier; regulation of tube size, open tracheal system; septate junction assembly.
44 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; adult segment; sensillum; eo support cell; plasma membrane part; presumptive embryonic/larval nervous system; adult mesothoracic segment; plasma membrane; SNc.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Carboxylesterase type B, conserved site; Carboxylesterase, type B.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 06-12 hour embryonic stages.