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|Flybase description||The gene Ca2+-channel protein α
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: voltage-gated calcium channel activity.
There is experimental evidence that it is involved in the biological process: epithelial fluid transport.
12 alleles are reported.
The phenotypes of these alleles are annotated with: cephalopharyngeal skeleton; NMJ bouton; neuromuscular junction; embryonic/larval tracheal system; longitudinal connective; wing; abdominal segmental nerve.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Ion transport; Voltage-dependent calcium channel, L-type, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit, IQ domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed during late pupal stages.