Flygut: an atlas of the Drosophila adult midgut

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Gene name Ca-alpha1D
Flybase description The gene Ca2+-channel protein α1 subunit D is referred to in FlyBase by the symbol Dmel\Ca-α1D (CG4894, FBgn0001991).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -28.7584 -20.5635 -33.047415 -32.6603 -51.147014 -34.4302 -25.98486 -27.979353
    Affimetrix absolute value 3.584 3.273 3.168 3.377 3.105 3.474 3.866 3.497
    Affymetric present call in "x" number of chips 1 0 0 0 0 1 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: voltage-gated calcium channel activity.
There is experimental evidence that it is involved in the biological process: epithelial fluid transport.
12 alleles are reported.
The phenotypes of these alleles are annotated with: cephalopharyngeal skeleton; NMJ bouton; neuromuscular junction; embryonic/larval tracheal system; longitudinal connective; wing; abdominal segmental nerve.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Ion transport; Voltage-dependent calcium channel, L-type, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit, IQ domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed during late pupal stages.