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|Flybase description||The gene discs overgrown is referred to in FlyBase by the symbol Dmel\dco (CG2048, FBgn0002413).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: kinase activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; regulation of biological process; anatomical structure development; phosphorus metabolic process; macromolecule modification; growth; cellular component organization or biogenesis; response to cocaine; rhythmic process; establishment of planar polarity.
97 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; dorsal thoracic disc; thoracic segment; wing hair; eo support cell; organ system; cephalopharyngeal skeleton; antennal segment; wing pouch.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.