Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name dco
Flybase description The gene discs overgrown is referred to in FlyBase by the symbol Dmel\dco (CG2048, FBgn0002413).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.7469 1.627 0.425903 -1.1595 -1.568786 -1.4496 0.43944 -1.407281
    Affimetrix absolute value 7.614 8.32 8.296 8.181 8.116 8.03 8.689 7.802
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: kinase activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; regulation of biological process; anatomical structure development; phosphorus metabolic process; macromolecule modification; growth; cellular component organization or biogenesis; response to cocaine; rhythmic process; establishment of planar polarity.
97 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; dorsal thoracic disc; thoracic segment; wing hair; eo support cell; organ system; cephalopharyngeal skeleton; antennal segment; wing pouch.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.