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|Flybase description||The gene lethal (3) malignant brain tumor is referred to in FlyBase by the symbol Dmel\l(3)mbt (CG5954, FBgn0002441).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: regulation of preblastoderm mitotic cell cycle; dendrite morphogenesis; negative regulation of gene expression; neuroblast proliferation; muscle organ development; negative regulation of transcription from RNA polymerase II promoter; syncytial nuclear migration.
25 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/larval brain.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Mbt repeat; Sterile alpha motif homology; Sterile alpha motif-type; Sterile alpha motif/pointed.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, in adult female stages.