Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pho
Flybase description The gene pleiohomeotic is referred to in FlyBase by the symbol Dmel\pho (CG17743, FBgn0002521).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.4301 1.4131 1.225901 -1.2444 -1.109827 -1.1322 -1.91312 0.327242
    Affimetrix absolute value 8.293 8.107 8.47 8.076 8.608 8.385 7.642 8.234
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: chromatin DNA binding; sequence-specific DNA binding; chromatin binding; DNA binding.
There is experimental evidence that it is involved in the biological process: gene silencing; regulation of transcription, DNA-dependent; negative regulation of gene expression; DNA topological change; chromatin silencing.
21 alleles are reported.
The phenotypes of these alleles are annotated with: unguis; antenna; sex comb; pupal abdomen.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.