Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name lace
Flybase description The gene lace is referred to in FlyBase by the symbol Dmel\lace (CG4162, FBgn0002524).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.4435 2.8559 2.208702 4.9071 1.548345 1.7238 -0.5862 2.114295
    Affimetrix absolute value 7.891 9.124 9.318 10.674 9.382 9.341 8.254 9.278
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: serine C-palmitoyltransferase activity.
There is experimental evidence that it is involved in the biological process: imaginal disc development; sphingolipid biosynthetic process.
33 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system subdivision; external compound sense organ; adult segment; thoracic segment; sensillum; peripheral nervous system; imaginal precursor; nervous system; compound cell cluster organ; larval thorax.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Aminotransferase, class I/classII; Aminotransferase, class-II, pyridoxal-phosphate binding site; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.