Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Lam
Flybase description The gene Lamin is referred to in FlyBase by the symbol Dmel\Lam (CG6944, FBgn0002525).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.5207 -2.1356 -2.266978 -3.19 -2.630515 -3.1791 -7.54683 -2.795489
    Affimetrix absolute value 6.594 6.54 7.009 6.725 7.374 6.935 5.67 6.762
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: anatomical structure development; multicellular organismal process; cellular component organization or biogenesis; organ morphogenesis; membrane organization; cell-cell signaling; organelle organization; localization; biological regulation; regulation of cellular macromolecule biosynthetic process; sensory organ development; chitin-based cuticle development; open tracheal system development; cell cycle; organ development; central nervous system development; cell fate commitment; digestive tract development; cellular localization.
36 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: nuclear part; organ system; envelope; external compound sense organ; non-connected developing system; nucleus; organ system subdivision; late extended germ band embryo; sensillum; rhabdomere; dorsal branch primordium; eo support cell; ganglionic branch primordium; spermatozoon; female germline cyst.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Filament; Intermediate filament protein; Intermediate filament, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages.