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|Flybase description||The gene leak is referred to in FlyBase by the symbol Dmel\lea (CG5481, FBgn0002543).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: axon guidance receptor activity; receptor activity.
There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; organ development; central nervous system development; biological regulation; organ morphogenesis; locomotion; cellular component organization or biogenesis; multicellular organismal process; regulation of biological process; embryonic heart tube development; ventral cord development; localization; regulation of multicellular organismal development.
50 alleles are reported.
The phenotypes of these alleles are annotated with 43 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; nervous system; embryonic/larval neuron; adult segment; hypodermal muscle of larval abdomen; cephalopharyngeal skeleton; commissure; A1-7 transverse muscle; primordium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.