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|Flybase description||The gene E(spl) region transcript m3 is referred to in FlyBase by the symbol Dmel\HLHm3 (CG8346, FBgn0002609).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding.
It is reported to be involved in the biological process: Notch signaling pathway; compound eye development; negative regulation of transcription from RNA polymerase II promoter.
8 alleles are reported.
The phenotype of these alleles is annotated with: scutellar bristle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Orange; Orange subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.