Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name HLHm3
Flybase description The gene E(spl) region transcript m3 is referred to in FlyBase by the symbol Dmel\HLHm3 (CG8346, FBgn0002609).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -37.5573 -2.9276 -1.741701 -3.127 -0.611045 -0.6546 -38.98636 -1.82258
    Affimetrix absolute value 3.232 6.099 7.408 6.771 8.427 8.205 3.293 7.382
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding.
It is reported to be involved in the biological process: Notch signaling pathway; compound eye development; negative regulation of transcription from RNA polymerase II promoter.
8 alleles are reported.
The phenotype of these alleles is annotated with: scutellar bristle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Orange; Orange subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.