Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name RpS3
Flybase description The gene Ribosomal protein S3 is referred to in FlyBase by the symbol Dmel\RpS3 (CG6779, FBgn0002622).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 30.0352 44.3126 29.172663 27.5059 18.759137 23.6214 26.96922 28.461943
    Affimetrix absolute value 13.315 13.078 13.034 13.161 12.983 13.108 13.281 13.041
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: oxidized purine base lesion DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity.
There is experimental evidence that it is involved in the biological process: negative regulation of neuron apoptosis; response to DNA damage stimulus; DNA repair; mitosis.
14 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; imaginal precursor; sensillum; anatomical structure; germarium; thoracic segment; dorsal thoracic disc; external compound sense organ; female germline cyst; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: K Homology; K Homology, prokaryotic type; K Homology, type 2; K homology domain-like, alpha/beta; Ribosomal protein S3, C-terminal; Ribosomal protein S3, conserved site; Ribosomal protein S3, eukaryotic/archaeal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.
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