|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene twine is referred to in FlyBase by the symbol Dmel\twe (CG4965, FBgn0002673).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein tyrosine phosphatase activity.
There is experimental evidence that it is involved in the biological process: regulation of meiotic cell cycle; spindle assembly involved in male meiosis; pole cell formation; regulation of syncytial blastoderm mitotic cell cycle; meiotic nuclear envelope disassembly; embryo development; male meiosis; cellularization; spindle assembly involved in female meiosis; spermatogenesis.
17 alleles are reported.
The phenotypes of these alleles are annotated with: yolk; trichogen cell; oocyte; spindle; tormogen cell; spermatocyte; oocyte nucleus.
It has one annotated transcript and one annotated polypeptide.
Protein features are: M-phase inducer phosphatase; Rhodanese-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.