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|Flybase description||The gene meiotic W68 is referred to in FlyBase by the symbol Dmel\mei-W68 (CG7753, FBgn0002716).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: DNA topoisomerase (ATP-hydrolyzing) activity.
There is experimental evidence that it is involved in the biological process: reciprocal meiotic recombination; oogenesis; early meiotic recombination nodule assembly; late meiotic recombination nodule assembly.
13 alleles are reported.
The phenotypes of these alleles are annotated with: early recombination nodule; late recombination nodule.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DNA topoisomerase VI, subunit A; Spo11/DNA topoisomerase VI, subunit A.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.