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|Flybase description||The gene Malic enzyme is referred to in FlyBase by the symbol Dmel\Men (CG10120, FBgn0002719).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; malate metabolic process.
66 alleles are reported.
The phenotype of these alleles is annotated with: eye.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Malic enzyme, N-terminal; Malic enzyme, NAD-binding; Malic enzyme, conserved site; Malic oxidoreductase; NAD(P)-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.