Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mus304
Flybase description The gene mutagen-sensitive 304 is referred to in FlyBase by the symbol Dmel\mus304 (CG7347, FBgn0002901).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -16.1257 -9.5932 -12.367096 -11.3026 -15.774611 -14.5983 -14.3079 -13.768028
    Affimetrix absolute value 4.403 4.366 4.594 4.892 4.797 4.697 4.712 4.497
    Affymetric present call in "x" number of chips 1 1 0 1 0 1 2 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATP-dependent DNA helicase activity.
There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; reciprocal meiotic recombination; female meiosis; DNA repair; telomere maintenance; mitotic cell cycle G2/M transition DNA damage checkpoint; regulation of syncytial blastoderm mitotic cell cycle; DNA damage checkpoint.
15 alleles are reported.
The phenotypes of these alleles are annotated with: cycle 13 embryo; wing disc; mitotic cell cycle; macrochaeta; cycle 12 embryo; mesothoracic tergum; cycle 14 embryo.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.