Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name nau
Flybase description The gene nautilus is referred to in FlyBase by the symbol Dmel\nau (CG10250, FBgn0002922).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -31.0807 -14.6118 -19.241614 -18.6981 -15.696316 -23.9508 -45.45006 -16.734855
    Affimetrix absolute value 3.469 3.767 3.932 4.17 4.803 3.989 3.067 4.203
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: DNA binding; sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: muscle organ development.
17 alleles are reported.
The phenotypes of these alleles are annotated with: myoblast; egg; A1-7 dorsal oblique muscle 4; midgut constriction; somatic mesoderm; presumptive embryonic/larval muscle system; abdominal 1 dorsal acute muscle 3; egg chamber; cardioblast; embryonic/larval somatic muscle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Myogenic basic muscle-specific protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-18 hour embryonic stages.