Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name opa
Flybase description The gene odd paired is referred to in FlyBase by the symbol Dmel\opa (CG1133, FBgn0003002).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.3814 -11.1504 -31.962744 -34.1324 -41.701589 -37.5681 -47.26343 -31.335313
    Affimetrix absolute value 2.941 4.162 3.202 3.295 3.392 3.331 2.996 3.303
    Affymetric present call in "x" number of chips 0 3 0 1 0 2 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: decapentaplegic receptor signaling pathway; eye-antennal disc morphogenesis; germ cell migration; midgut development.
41 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: multicellular structure; primordium; organ system; embryonic segment; late extended germ band embryo; anatomical structure; cuticle; imaginal precursor; extended germ band embryo; integumentary system; midgut constriction; heart primordium; external compound sense organ; antennal segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages.