Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name otu
Flybase description The gene ovarian tumor is referred to in FlyBase by the symbol Dmel\otu (CG12743, FBgn0003023).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -51.113 -35.1282 -45.869218 -59.9558 -71.998539 -73.0851 -69.54025 -58.025574
    Affimetrix absolute value 2.74 2.499 2.702 2.497 2.603 2.373 2.433 2.428
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: positive regulation of DNA endoreduplication.
63 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; female germline cyst; multicellular structure; anatomical structure; egg; germarium; nuclear part; cytoplasmic part; germline cell; chorion; nuclear chromosome; fusome.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Ovarian tumour, otubain; Tudor domain; Tudor subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed in adult female stages.