|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene pebble is referred to in FlyBase by the symbol Dmel\pbl (CG8114, FBgn0003041).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: guanyl-nucleotide exchange factor activity.
There is experimental evidence for 14 unique biological process terms, many of which group under: anatomical structure development; cell cycle; cell division; cell cycle process; cellular component organization or biogenesis; biological regulation; localization; regulation of developmental process; embryonic hindgut morphogenesis; mesoderm morphogenesis; cell adhesion; cytokinesis after meiosis; establishment of protein localization; regulation of multicellular organismal development.
43 alleles are reported.
The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system subdivision; primordium; external compound sense organ; germ layer; cytoplasmic part; adult segment; organelle; ventral nerve cord primordium; presumptive embryonic/larval nervous system; adult mesothoracic segment.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: BRCT; Dbl homology (DH) domain; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.