Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pc
Flybase description The gene Polycomb is referred to in FlyBase by the symbol Dmel\Pc (CG32443, FBgn0003042).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.8149 -7.2479 -10.382692 -11.4549 -18.583875 -15.3196 -15.29496 -17.504235
    Affimetrix absolute value 4.67 4.771 4.819 4.886 4.554 4.647 4.643 4.139
    Affymetric present call in "x" number of chips 2 3 3 3 0 2 2 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: chromatin binding; methylated histone residue binding.
There is experimental evidence that it is involved in the biological process: gene silencing; regulation of transcription, DNA-dependent; specification of segmental identity, abdomen; neuron remodeling; syncytial blastoderm mitotic cell cycle; neurogenesis.
92 alleles are reported.
The phenotypes of these alleles are annotated with 35 unique terms, many of which group under: adult segment; embryonic abdomen; embryonic segment; organ system subdivision; thoracic segment; primordium; late extended germ band embryo; adult abdominal segment; non-connected developing system; embryonic head; abdominal segment 7; presumptive embryonic/larval nervous system; midgut constriction; embryonic abdominal segment 4; larval abdominal segment; antennal segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Chromo domain; Chromo domain subgroup; Chromo domain-like; Chromo domain/shadow.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.