Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Pcl
Flybase description The gene Polycomblike is referred to in FlyBase by the symbol Dmel\Pcl (CG5109, FBgn0003044).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.1318 -6.4316 -9.011435 -10.5089 -14.320122 -10.6303 -11.67151 -13.543219
    Affimetrix absolute value 5.069 4.949 5.019 5.022 4.925 5.156 5.038 4.561
    Affymetric present call in "x" number of chips 1 3 3 3 3 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; protein binding; DNA binding.
There is experimental evidence that it is involved in the biological process: chromatin modification; negative regulation of transcription, DNA-dependent; neurogenesis.
40 alleles are reported.
The phenotypes of these alleles are annotated with 33 unique terms, many of which group under: adult segment; embryonic abdomen; organ system subdivision; embryonic segment; larval abdominal segment; organ system; abdominal segment 7; adult mesothoracic segment; gland; larval abdominal segment 5; midgut constriction; embryonic abdominal segment 4; antennal segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Tudor domain; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.