Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name peb
Flybase description The gene pebbled is referred to in FlyBase by the symbol Dmel\peb (CG12212, FBgn0003053).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -17.4255 -2.1073 -1.696569 -0.6017 -2.304149 -1.8304 -12.35564 -2.320238
    Affimetrix absolute value 4.323 6.549 7.44 8.066 7.604 7.713 5.074 7.074
    Affymetric present call in "x" number of chips 0 2 3 3 3 3 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: anatomical structure development; biological regulation; multicellular organismal process; sensory organ development; embryonic development via the syncytial blastoderm; open tracheal system development; tissue homeostasis; cellular component organization or biogenesis; ommatidial rotation; anterior/posterior axis specification.
26 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; cuticle; cephalopharyngeal skeleton; extended germ band embryo; organ system subdivision; taenidial fold; external compound sense organ; embryonic/larval tracheal system; pharyngeal sclerite; compound cell cluster organ; gland; rhabdomere; spiracle; late extended germ band embryo.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages.