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|Flybase description||The gene pole hole is referred to in FlyBase by the symbol Dmel\phl (CG2845, FBgn0003079).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein serine/threonine kinase activity.
There is experimental evidence for 19 unique biological process terms, many of which group under: anatomical structure development; biological regulation; regulation of biological process; cellular process involved in reproduction; hemocyte differentiation; multicellular organismal reproductive process; signaling; post-embryonic organ morphogenesis; macromolecule modification; positive regulation of cell proliferation; organ development; anterior/posterior axis specification; instar larval development.
93 alleles are reported.
The phenotypes of these alleles are annotated with 60 unique terms, many of which group under: organ system subdivision; external compound sense organ; adult segment; embryonic abdomen; adult mesothoracic segment; peripheral nervous system; hemocyte; embryonic segment; spermatocyte; primordium.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protein kinase C-like, phorbol ester/diacylglycerol binding; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Raf-like Ras-binding; Serine-threonine/tyrosine-protein kinase; Serine/threonine-protein kinase, active site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.