Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pk
Flybase description The gene prickle is referred to in FlyBase by the symbol Dmel\pk (CG11084, FBgn0003090).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.518 -11.3474 -18.58347 -33.5445 -35.044692 -29.8327 -27.42846 -22.854504
    Affimetrix absolute value 4.897 4.138 3.984 3.337 3.634 3.664 3.805 3.759
    Affymetric present call in "x" number of chips 3 3 2 0 1 2 1 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding.
There is experimental evidence that it is involved in the biological process: establishment or maintenance of cell polarity; establishment of imaginal disc-derived wing hair orientation; establishment of ommatidial planar polarity; morphogenesis of a polarized epithelium.
102 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; thoracic segment; appendage segment; external compound sense organ; organ system; wing hair; compound cell cluster organ; metatarsus; integumentary specialisation; peripheral nervous system.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: PET domain; Zinc finger, LIM-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.