Flygut: an atlas of the Drosophila adult midgut

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Gene name Pkc98E
Flybase description The gene Protein C kinase 98E is referred to in FlyBase by the symbol Dmel\Pkc98E (CG1954, FBgn0003093).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.7381 -5.3688 -10.688101 -7.4841 -16.468774 -10.7685 -7.44569 -13.240705
    Affimetrix absolute value 5.899 5.195 4.788 5.519 4.753 5.137 5.661 4.621
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein kinase C activity; diacylglycerol binding.
There is experimental evidence that it is involved in the biological process: response to ethanol.
11 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: AGC-kinase, C-terminal; Diacylglycerol/phorbol-ester binding; Protein kinase C, delta/epsilon/eta/theta types; Protein kinase C-like, phorbol ester/diacylglycerol binding; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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