Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pnt
Flybase description The gene pointed is referred to in FlyBase by the symbol Dmel\pnt (CG17077, FBgn0003118).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -26.9071 -9.1928 -19.25488 -15.7211 -32.284659 -17.0976 -45.65792 -22.097581
    Affimetrix absolute value 3.683 4.423 3.933 4.467 3.789 4.567 3.057 3.841
    Affymetric present call in "x" number of chips 1 3 1 2 2 3 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 18 unique biological process terms, many of which group under: anatomical structure development; biological regulation; open tracheal system development; organ development; localization; regulation of biological process; regulation of developmental process; post-embryonic organ morphogenesis; positive regulation of cell proliferation; cellular component organization or biogenesis; anterior/posterior axis specification.
114 alleles are reported.
The phenotypes of these alleles are annotated with 94 unique terms, many of which group under: organ system subdivision; commissure; nervous system; multi-cell-component structure; primordium; external compound sense organ; abdominal lateral pentascolopidial chordotonal organ lch5; larval abdominal segment 5; late extended germ band embryo; adult segment.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Ets; Sterile alpha motif homology; Sterile alpha motif-type; Sterile alpha motif/pointed; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.