Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Poxm
Flybase description The gene Pox meso is referred to in FlyBase by the symbol Dmel\Poxm (CG9610, FBgn0003129).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.5996 -8.3989 -13.089026 -16.5051 -20.433654 -20.3733 -15.47035 -13.224559
    Affimetrix absolute value 5.704 4.575 4.535 4.344 4.414 4.213 4.604 4.552
    Affymetric present call in "x" number of chips 2 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: larval somatic muscle development.
9 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: hypodermal muscle of larval abdomen; organ system; A1-7 oblique muscle; larval abdominal segment; A1-7 transverse muscle; organ system subdivision; adult segment; A1-7 ventral oblique muscle 4; A1-7 ventral oblique muscle 1; adult abdominal myoblast; external compound sense organ; antennal segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeodomain-like; Paired box protein, N-terminal; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.