Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Poxn
Flybase description The gene Pox neuro is referred to in FlyBase by the symbol Dmel\Poxn (CG8246, FBgn0003130).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -54.4241 -23.7898 -27.497308 -39.2832 -37.225548 -54.1936 -46.83738 -31.085474
    Affimetrix absolute value 2.656 3.059 3.411 3.095 3.557 2.808 3.002 3.323
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: sensory organ development; antennal morphogenesis; adult feeding behavior; imaginal disc-derived wing morphogenesis; imaginal disc-derived leg morphogenesis; response to water; male courtship behavior.
37 alleles are reported.
The phenotypes of these alleles are annotated with 49 unique terms, many of which group under: organ system subdivision; adult segment; peripheral nervous system; nervous system; gustatory sensory organ; adult mesothoracic segment; external compound sense organ; antennal segment; metathoracic les3 neuron; abdominal 4 ventral sensillum campaniformium vc5; larval abdominal segment 5; mouthpart; abdominal 7 ventral sensillum campaniformium vc5; metathoracic posterior fascicle neuron.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeodomain-like; Paired box protein, N-terminal; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages.