Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pum
Flybase description The gene pumilio is referred to in FlyBase by the symbol Dmel\pum (CG9755, FBgn0003165).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.9315 -5.376 -23.889119 -19.6699 -48.139759 -19.5808 -23.00251 -31.007448
    Affimetrix absolute value 3.465 5.216 3.648 4.13 3.209 4.301 4.028 3.375
    Affymetric present call in "x" number of chips 0 3 1 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: translation repressor activity, nucleic acid binding; mRNA 3'-UTR binding.
There is experimental evidence that it is involved in the biological process: regulation of synaptic transmission; synaptic transmission; dendrite morphogenesis; pole cell migration; long-term memory; head involution; regulation of synaptic growth at neuromuscular junction.
134 alleles are reported.
The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: embryonic abdomen; organ system; organ system subdivision; embryonic segment; female germline cyst; peripheral nervous system; germarium; embryonic/larval neuron; cephalopharyngeal skeleton; portion of tissue.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Armadillo-like helical; Armadillo-type fold; Pumilio RNA-binding repeat.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.