Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Ras64B
Flybase description The gene Ras oncogene at 64B is referred to in FlyBase by the symbol Dmel\Ras64B (CG1167, FBgn0003206).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.494 1.4012 -2.29078 -1.2927 -3.277647 -1.5258 2.67625 -1.773249
    Affimetrix absolute value 10.548 8.067 6.993 8.026 7.074 7.957 9.953 7.563
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: GTP catabolic process; small GTPase mediated signal transduction.
28 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; nervous system; embryonic head; adult segment; histaminergic neuron; embryonic tagma; adult mesothoracic segment; thoracic segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ras type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed within 12-24 hour embryonic stages, during late larval stages.