Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name rb
Flybase description The gene ruby is referred to in FlyBase by the symbol Dmel\rb (CG11427, FBgn0003210).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.8363 -2.0913 -3.997781 -4.8225 -7.694018 -6.5386 -3.56839 -5.80337
    Affimetrix absolute value 6.915 6.587 6.19 6.129 5.822 5.865 6.764 5.757
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding; protein transporter activity.
There is experimental evidence that it is involved in the biological process: regulation of protein ubiquitination; determination of adult lifespan; ommochrome biosynthetic process.
18 alleles are reported.
The phenotypes of these alleles are annotated with: Malpighian tubule; testis pigment cell; secondary pigment cell pigment granule; ocellus pigment granule; tertiary pigment cell pigment granule; photoreceptor cell pigment granule; pigment cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Adaptor protein complex AP-3, beta subunit; Armadillo-like helical; Armadillo-type fold; Clathrin/coatomer adaptor, adaptin-like, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, in adult female stages.