Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name rk
Flybase description The gene rickets is referred to in FlyBase by the symbol Dmel\rk (CG8930, FBgn0003255).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -46.872 -36.2756 -52.359527 -69.336 -79.683209 -81.8016 -78.20504 -62.643443
    Affimetrix absolute value 2.862 2.447 2.481 2.28 2.453 2.209 2.264 2.31
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: G-protein coupled receptor activity; protein-hormone receptor activity; neuropeptide receptor activity.
There is experimental evidence that it is involved in the biological process: epithelial to mesenchymal transition; regulation of chitin-based cuticle tanning.
33 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: adult segment; organ system subdivision; organ system; thoracic segment; adult mesothoracic segment; cuticle; sensillum; nervous system; adult cuticle; appendage segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Armadillo; GPCR, rhodopsin-like superfamily; GPCR, rhodopsin-like, 7TM; Glycoprotein hormone receptor; Leucine-rich repeat; Leucine-rich repeat, typical subtype.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed at stages throughout the pupal period.