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|Flybase description||The gene rickets is referred to in FlyBase by the symbol Dmel\rk (CG8930, FBgn0003255).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: G-protein coupled receptor activity; protein-hormone receptor activity; neuropeptide receptor activity.
There is experimental evidence that it is involved in the biological process: epithelial to mesenchymal transition; regulation of chitin-based cuticle tanning.
33 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: adult segment; organ system subdivision; organ system; thoracic segment; adult mesothoracic segment; cuticle; sensillum; nervous system; adult cuticle; appendage segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Armadillo; GPCR, rhodopsin-like superfamily; GPCR, rhodopsin-like, 7TM; Glycoprotein hormone receptor; Leucine-rich repeat; Leucine-rich repeat, typical subtype.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed at stages throughout the pupal period.