|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene roughest is referred to in FlyBase by the symbol Dmel\rst (CG4125, FBgn0003285).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: PDZ domain binding.
There is experimental evidence that it is involved in the biological process: compound eye development; lateral inhibition; regulation of striated muscle tissue development; compound eye morphogenesis.
31 alleles are reported.
The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: organ system subdivision; external compound sense organ; antennal segment; adult segment; peripheral nervous system; non-connected developing system; primordium; nervous system; ommatidial precursor cluster; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: CD80-like, immunoglobulin C2-set; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.