Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name rst
Flybase description The gene roughest is referred to in FlyBase by the symbol Dmel\rst (CG4125, FBgn0003285).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -25.5959 -16.1023 -27.087866 -29.9719 -40.012102 -31.2281 -24.99328 -27.59867
    Affimetrix absolute value 3.777 3.628 3.424 3.486 3.473 3.604 3.908 3.464
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: PDZ domain binding.
There is experimental evidence that it is involved in the biological process: compound eye development; lateral inhibition; regulation of striated muscle tissue development; compound eye morphogenesis.
31 alleles are reported.
The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: organ system subdivision; external compound sense organ; antennal segment; adult segment; peripheral nervous system; non-connected developing system; primordium; nervous system; ommatidial precursor cluster; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: CD80-like, immunoglobulin C2-set; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.