Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ru
Flybase description The gene roughoid is referred to in FlyBase by the symbol Dmel\ru (CG1214, FBgn0003295).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -42.3418 -25.9165 -33.268901 -45.0384 -52.464185 -41.8232 -43.61569 -38.704331
    Affimetrix absolute value 3.008 2.934 3.177 2.907 3.054 3.181 3.118 3.013
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: serine-type peptidase activity.
There is experimental evidence that it is involved in the biological process: compound eye photoreceptor fate commitment; heart process; compound eye cone cell fate commitment; epithelial cell migration, open tracheal system.
19 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor; eye; egg; cone cell; adult heart chamber; eye photoreceptor cell; wing; ommatidium; embryonic/larval ganglionic branch; pigment cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase S54, rhomboid; Peptidase S54, rhomboid domain; Peptidase S54, rhomboid, metazoan.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed at stages throughout the pupal period.