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|Flybase description||The gene shadow is referred to in FlyBase by the symbol Dmel\sad (CG14728, FBgn0003312).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ecdysteroid 2-hydroxylase activity.
There is experimental evidence that it is involved in the biological process: motor axon guidance; central nervous system development; dorsal closure; ecdysone biosynthetic process; head involution; midgut development.
14 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; nervous system; non-connected developing system; presumptive embryonic/larval nervous system; portion of tissue; cuticle; multi-cell-component structure; integumentary system; cephalopharyngeal skeleton; axon; commissure.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.