Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name sbr
Flybase description The gene small bristles is referred to in FlyBase by the symbol Dmel\sbr (CG1664, FBgn0003321).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.0563 -0.3616 -2.116673 -1.7737 -3.934644 -1.9154 -2.16673 -3.647063
    Affimetrix absolute value 6.839 7.581 7.15 7.576 6.863 7.631 7.439 6.682
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleotide binding.
There is experimental evidence that it is involved in the biological process: nuclear export; mRNA export from nucleus; mRNA polyadenylation; poly(A)+ mRNA export from nucleus.
35 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system subdivision; adult segment; organ system; sensillum; hypodermal muscle of larval abdomen; adult mesothoracic segment; multi-cell-component structure; thoracic segment; organelle; intracellular membrane-bounded organelle; larval abdominal segment; integumentary specialisation; A1-7 ventral longitudinal muscle 3.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Leucine-rich repeat; Nuclear transport factor 2; Nuclear transport factor 2, Eukaryote; Nucleotide-binding, alpha-beta plait; TAP, C-terminal; UBA-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.