Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sca
Flybase description The gene scabrous is referred to in FlyBase by the symbol Dmel\sca (CG17579, FBgn0003326).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -42.3242 -28.7672 -38.314875 -41.5974 -50.056903 -41.5317 -52.02428 -36.731606
    Affimetrix absolute value 3.008 2.809 2.928 3.044 3.125 3.191 2.852 3.097
    Affymetric present call in "x" number of chips 0 0 0 0 0 3 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: signal transducer activity.
There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; compound eye development; imaginal disc-derived wing margin morphogenesis; nervous system development; ommatidial rotation; bristle morphogenesis.
71 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; peripheral nervous system; eo support cell; sensillum; nervous system; acrostichal bristle; anchoring junction; imaginal precursor; adult cuticle; antennal segment; plasma membrane part.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Fibrinogen, alpha/beta/gamma chain, C-terminal globular; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2; Fibrinogen, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.