Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sce
Flybase description The gene Sex combs extra is referred to in FlyBase by the symbol Dmel\Sce (CG5595, FBgn0003330).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.0617 -5.26 -5.813595 -6.7127 -6.975825 -7.2272 -7.51097 -5.832524
    Affimetrix absolute value 6.092 5.225 5.646 5.645 5.964 5.778 5.661 5.701
    Affymetric present call in "x" number of chips 3 2 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: germarium-derived female germ-line cyst encapsulation; ovarian follicle cell stalk formation; sex comb development; multicellular organismal development; chromatin silencing; sister chromatid cohesion; neurogenesis.
10 alleles are reported.
The phenotypes of these alleles are annotated with: larval abdominal segment 7; metathoracic ventral denticle belt; abdominal 4 ventral denticle belt; prothoracic ventral denticle belt; mesothoracic tergum; embryonic thoracic segment; mesothoracic ventral denticle belt; embryonic abdominal segment; denticle belt.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.