Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sd
Flybase description The gene scalloped is referred to in FlyBase by the symbol Dmel\sd (CG8544, FBgn0003345).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.15 1.0689 -1.658289 -1.5918 -2.754237 -1.7962 -1.99265 -2.056828
    Affimetrix absolute value 7.33 7.712 7.467 7.74 7.327 7.723 7.561 7.228
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: somatic muscle development; sensory organ development; stem cell proliferation; imaginal disc-derived wing morphogenesis; imaginal disc-derived leg morphogenesis; cardiac muscle cell development; compound eye morphogenesis.
201 alleles are reported.
The phenotypes of these alleles are annotated with 39 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; hypodermal muscle of larval abdomen; external compound sense organ; sensillum; larval abdominal segment; larval thorax; embryonic/larval cardial cell; A1-7 ventral oblique muscle 4; lobula complex; midgut constriction; dorsal thoracic disc.
It has 16 annotated transcripts and 16 annotated polypeptides.
Protein features are: TEA/ATTS; Transcriptional enhancer factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 06-18 hour embryonic stages.