Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name shf
Flybase description The gene shifted is referred to in FlyBase by the symbol Dmel\shf (CG3135, FBgn0003390).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.2388 -3.4137 -0.328683 -11.3166 -8.448215 -8.6282 -5.26197 -2.427617
    Affimetrix absolute value 10.093 5.87 8.176 4.92 5.7 5.612 6.189 6.983
    Affymetric present call in "x" number of chips 3 3 3 1 1 2 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: smoothened signaling pathway; regulation of smoothened signaling pathway; protein stabilization; Wnt receptor signaling pathway.
20 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; external compound sense organ; organ system; integumentary plate; compound cell cluster organ; sensillum; wing cell; peripheral nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: EGF-like region, conserved site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; WIF domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed at stages throughout the pupal period.