Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name shi
Flybase description The gene shibire is referred to in FlyBase by the symbol Dmel\shi (CG18102, FBgn0003392).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.1821 -2.5251 -3.525414 -1.8729 -6.089664 -3.0337 -3.76589 -4.388106
    Affimetrix absolute value 5.577 6.284 6.389 7.509 6.199 6.963 6.642 6.191
    Affymetric present call in "x" number of chips 0 3 3 3 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin binding; microtubule binding.
There is experimental evidence for 34 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular component organization or biogenesis; localization; multicellular organismal reproductive process; regulation of biological process; synaptic transmission; learning; mating; memory; associative learning; cellular process involved in reproduction.
75 alleles are reported.
The phenotypes of these alleles are annotated with 69 unique terms, many of which group under: organ system subdivision; external compound sense organ; adult segment; peripheral nervous system; nervous system; female germline cyst; antennal segment; late extended germ band embryo; adult mesothoracic segment; muscle founder cell.
It has 12 annotated transcripts and 12 annotated polypeptides.
Protein features are: Dynamin; Dynamin GTPase effector; Dynamin central domain; Dynamin, GTPase domain; Dynamin, GTPase region, conserved site; GTPase effector domain, GED; Pleckstrin homology domain; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.