Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sl
Flybase description The gene small wing is referred to in FlyBase by the symbol Dmel\sl (CG4200, FBgn0003416).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.0833 0.5065 -0.545979 -1.3092 -2.307468 -1.7947 -1.70901 -1.977869
    Affimetrix absolute value 7.371 7.822 7.925 8.014 7.564 7.725 7.822 7.302
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: phosphatidylinositol phospholipase C activity.
There is experimental evidence that it is involved in the biological process: border follicle cell migration.
23 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor cell R7; eye; interommatidial bristle; primary pigment cell; primary segmental branch; cone cell; eye photoreceptor cell; wing; ommatidium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; EF-hand-like domain; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma; Phosphoinositide phospholipase C; Phospholipase C, phosphatidylinositol-specific , X domain; Phospholipase C, phosphatidylinositol-specific, Y domain; Phospholipase C, phosphoinositol-specific, EF-hand-like; Pleckstrin homology domain; Pleckstrin homology-type; SH2 motif; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.