Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name slo
Flybase description The gene slowpoke is referred to in FlyBase by the symbol Dmel\slo (CG10693, FBgn0003429).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.5301 -10.5909 -15.413405 -2.8705 -2.313742 -15.125 -27.20459 -4.63921
    Affimetrix absolute value 4.767 4.259 4.231 6.889 7.609 4.652 3.788 6.105
    Affymetric present call in "x" number of chips 0 0 0 3 3 0 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; calcium-activated potassium channel activity.
There is experimental evidence that it is involved in the biological process: male courtship behavior, veined wing generated song production; circadian rhythm; potassium ion transport; circadian behavior; response to drug.
40 alleles are reported.
The phenotypes of these alleles are annotated with: neuron; neuromuscular junction; indirect flight muscle.
It has 18 annotated transcripts and 18 annotated polypeptides.
Protein features are: Ion transport; Ion transport 2; NAD(P)-binding domain; Potassium channel, calcium-activated, BK, alpha subunit; Voltage-dependent potassium channel.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.