Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name so
Flybase description The gene sine oculis is referred to in FlyBase by the symbol Dmel\so (CG11121, FBgn0003460).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -22.9244 -26.7737 -45.254669 -50.4628 -81.897612 -60.7499 -45.47297 -51.921307
    Affimetrix absolute value 3.951 2.881 2.689 2.735 2.404 2.639 3.049 2.598
    Affymetric present call in "x" number of chips 3 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: entrainment of circadian clock; ring gland development; glial cell migration; circadian rhythm; optic lobe placode formation; compound eye morphogenesis; spermatogenesis; Bolwig's organ morphogenesis.
55 alleles are reported.
The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system subdivision; nervous system; multi-cell-component structure; adult segment; external compound sense organ; peripheral nervous system; adult brain; presumptive embryonic/larval nervous system; primordium; larval head segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.