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|Flybase description||The gene spire is referred to in FlyBase by the symbol Dmel\spir (CG10076, FBgn0003475).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; microtubule binding.
There is experimental evidence that it is involved in the biological process: chorion-containing eggshell formation; actin filament-based process; actin nucleation; regulation of cytoskeleton organization; pole plasm assembly; pole plasm RNA localization; karyosome formation.
51 alleles are reported.
The phenotypes of these alleles are annotated with: karyosome; egg chamber; oocyte nucleus.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Actin-binding WH2; KIND; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.