Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name spir
Flybase description The gene spire is referred to in FlyBase by the symbol Dmel\spir (CG10076, FBgn0003475).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.7373 -2.3372 -4.750573 -3.3795 -5.781328 -4.5439 -6.31087 -5.523745
    Affimetrix absolute value 4.635 6.413 5.977 6.641 6.258 6.385 5.896 5.869
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; microtubule binding.
There is experimental evidence that it is involved in the biological process: chorion-containing eggshell formation; actin filament-based process; actin nucleation; regulation of cytoskeleton organization; pole plasm assembly; pole plasm RNA localization; karyosome formation.
51 alleles are reported.
The phenotypes of these alleles are annotated with: karyosome; egg chamber; oocyte nucleus.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Actin-binding WH2; KIND; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.