Flygut: an atlas of the Drosophila adult midgut

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Gene name spn-A
Flybase description The gene spindle A is referred to in FlyBase by the symbol Dmel\spn-A (CG7948, FBgn0003479).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.7833 -5.2267 -7.169856 -7.177 -7.054038 -6.4412 -9.20761 -7.980528
    Affimetrix absolute value 6.152 5.255 5.355 5.581 5.948 5.9 5.363 5.259
    Affymetric present call in "x" number of chips 3 3 2 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: recombinase activity.
There is experimental evidence that it is involved in the biological process: germarium-derived oocyte fate determination; female meiosis; double-strand break repair via synthesis-dependent strand annealing; polarity specification of dorsal/ventral axis; intracellular mRNA localization; cell cycle checkpoint; oogenesis; polarity specification of anterior/posterior axis; karyosome formation.
29 alleles are reported.
The phenotypes of these alleles are annotated with: germline cyst; chorion; egg; oocyte; presumptive oocyte; karyosome; egg chamber; dorsal appendage; nurse cell; synaptonemal complex.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: ATPase, AAA+ type, core; DNA recombination and repair protein Rad51, C-terminal; DNA recombination and repair protein, RecA-like; DNA recombination/repair protein Rad51; DNA recombination/repair protein RecA, monomer-monomer interface; DNA recombination/repair protein RecA/RadB, ATP-binding domain; DNA repair Rad51/transcription factor NusA, alpha-helical; Helix-hairpin-helix DNA-binding motif, class 1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.