Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name spo
Flybase description The gene spook is referred to in FlyBase by the symbol Dmel\spo (CG10594, FBgn0003486).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -67.7838 -28.0384 -49.727914 -57.456 -75.325758 -75.2926 -74.43646 -52.766755
    Affimetrix absolute value 2.329 2.827 2.548 2.551 2.549 2.332 2.344 2.554
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: electron carrier activity.
There is experimental evidence that it is involved in the biological process: central nervous system development; dorsal closure; embryonic digestive tract development; embryonic development via the syncytial blastoderm; cuticle development; oogenesis; ecdysone biosynthetic process; head involution; midgut development.
14 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; multicellular structure; non-connected developing system; organ system subdivision; nervous system; cuticle; presumptive embryonic/larval nervous system; integumentary system; portion of tissue; multi-cell-component structure.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected.
Peak expression observed within 00-06 hour embryonic stages.