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|Flybase description||The gene Btk family kinase at 29A is referred to in FlyBase by the symbol Dmel\Btk29A (CG8049, FBgn0003502).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein tyrosine kinase activity.
There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; multicellular organismal reproductive process; cellular process involved in reproduction; ovarian nurse cell to oocyte transport; gland morphogenesis; learning; determination of adult lifespan; cell cycle; learning or memory; cell cycle process; organ development; biological regulation; embryonic development via the syncytial blastoderm; open tracheal system development; imaginal disc-derived male genitalia development; actin filament-based process; aging.
51 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; female germline cyst; embryonic foregut; integumentary specialisation; cuticle; portion of tissue; non-connected developing system; taenidial fold; organelle; mouthpart; egg; primordium; spiracle.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; SH2 motif; Serine-threonine/tyrosine-protein kinase; Src homology-3 domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, non-receptor Btk29A; Zinc finger, Btk motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages.