Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Btk29A
Flybase description The gene Btk family kinase at 29A is referred to in FlyBase by the symbol Dmel\Btk29A (CG8049, FBgn0003502).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -25.228 -7.6982 -36.978216 -47.0806 -40.331973 -22.5851 -7.85997 -33.638892
    Affimetrix absolute value 3.776 4.726 2.976 2.838 3.448 4.066 5.614 3.25
    Affymetric present call in "x" number of chips 1 3 0 0 0 2 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein tyrosine kinase activity.
There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; multicellular organismal reproductive process; cellular process involved in reproduction; ovarian nurse cell to oocyte transport; gland morphogenesis; learning; determination of adult lifespan; cell cycle; learning or memory; cell cycle process; organ development; biological regulation; embryonic development via the syncytial blastoderm; open tracheal system development; imaginal disc-derived male genitalia development; actin filament-based process; aging.
51 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; female germline cyst; embryonic foregut; integumentary specialisation; cuticle; portion of tissue; non-connected developing system; taenidial fold; organelle; mouthpart; egg; primordium; spiracle.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; SH2 motif; Serine-threonine/tyrosine-protein kinase; Src homology-3 domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, non-receptor Btk29A; Zinc finger, Btk motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages.