Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Su(var)3-7
Flybase description The gene Suppressor of variegation 3-7 is referred to in FlyBase by the symbol Dmel\Su(var)3-7 (CG8599, FBgn0003598).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -28.2632 -17.0783 -27.434547 -26.3184 -47.482843 -27.3027 -31.7546 -31.354286
    Affimetrix absolute value 3.588 3.535 3.427 3.679 3.197 3.812 3.576 3.313
    Affymetric present call in "x" number of chips 0 1 0 2 0 2 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding.
There is experimental evidence that it is involved in the biological process: dosage compensation, by inactivation of X chromosome.
48 alleles are reported.
The phenotypes of these alleles are annotated with: macrochaeta; humeral bristle; sex comb; wing; ommatidium.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: BESS motif; Zinc finger, C2H2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.