Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name svp
Flybase description The gene seven up is referred to in FlyBase by the symbol Dmel\svp (CG11502, FBgn0003651).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -31.0115 -22.7273 -36.865296 -47.8657 -67.607456 -58.0098 -43.66295 -41.001171
    Affimetrix absolute value 3.465 3.118 3.014 2.807 2.708 2.705 3.107 2.937
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: phototaxis; neuron-neuron synaptic transmission; cardioblast cell fate determination.
62 alleles are reported.
The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system subdivision; external compound sense organ; embryonic/larval neuron; peripheral nervous system; nervous system; embryonic hindgut; anterior Malpighian tubule; ventral nerve cord primordium; ostia; GW neuron; primordium.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Steroid hormone receptor; Transcription factor COUP; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.